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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd7f25cdd2422a8300bda77e5446819f2882458326896dcf99605514a130938' 
  AND token = '4XNetciztGMf/Lej+iTnmEi8aiXUFTymCeNDOHZ62jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}