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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00bc6701750b99865458a22b4f8b978328af4a442fc29eab4b797a37de370a67' 
  AND token = '2OEbhiODz9nmY3EzzEqYyc4lY+oLgn+EAZnKuxjsg44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}