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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480258b29c4918a9f46bf57af6a96d25ef1750309c0cdf8e335645d0405e045b' 
  AND token = 'ixl7nvxi4KWbp8a4bKPDQ8vM0BELTzAfxrjYGhTPpvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}