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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50495fd2b92d8533fa8ab80f36b09079be067072e5d4b1821661eb7a7e7c21a2' 
  AND token = 'rhzfh7h69JxrrXDVo1xqr1aafCkkVnBzeQGRNMfAYDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}