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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449e3c637f2f2a035ce5cf471724cabfeee135bfd7aa9ba2628d24eace746ce3' 
  AND token = 'oL7Jl8AOOI5SKvjpdW6if3BCsXnQMLi21oYrwtD6KRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}