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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57bf761af25b3e99ac0759b32b00c6d4ff83769ec17aed58b8512d6ae395cf9' 
  AND token = 'zlbPTtn6FoREt1xl0NIxd7F+4gsGpA/s6DYlov3nHZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}