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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75565e0be6ceb12069ad19f2d2572bc6d24bdc63325d1793ac331e3459751861' 
  AND token = '5E1+f6zUn+U31B6N20CmwDHfYyvaLkqi6/1j5fj6kB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}