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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b7bfdfae2f6aa2dfac4b58730a1a39b954822f3905b4181dd41741dc551df0' 
  AND token = '7O1flYxA8xq7RQ+AoxKqzinlx0rwbUGhZ4ffT6wwtQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}