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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbf27a29a88323308066f5d9eaef8016c332668bebfd5c0249ccc7d00f66ec86' 
  AND token = 'kTm0D7vuq5bhvy+KR+OwUNRtP7lEPr7igBs3wmGRrXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}