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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df9c57fe558503b6bb729a98df8c157b776f3943a200b4a4e27a0f11b549cf6f' 
  AND token = '5/sM5cL7SKAMVXfJS0WK2ZdFH9WBuDbUXrBP6qs4gc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}