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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd14eb19da6aa30599e05f7ead551fc78603ce4056caa33fc249cbe7db7d2a8df' 
  AND token = 'La+Py6aLfCPfF5S+Qe4B90zz4hX0BmB5yQ+DJfO3pNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}