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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77806d10dfa301978a5261f75a0f98fac80f00893f8b06bb406b668a69e42012' 
  AND token = '42MM6r3plozrWe7gujYqxvBfcFN97wkVU2evhjI2J1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}