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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7353f487b9f7051c07202aa3abc501b5cab0ffc05a72f4906bcefb146c37924d' 
  AND token = 'lT06rba3pkg5vbhr4VRroKfW6mhM65NjSho7tU5snBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}