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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d5c78ae3a9176e4ca6c1a4f01380a20ece768c003d0473031428796507f3bf2' 
  AND token = 'VLQcTKm15K13DN0sLyPdkAOIBeNPQ48dE0l3iXDkdLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}