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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443a61b112a22b3b8a512f44378c6c0327a00065e3e70bb0fead25f80ca60e03' 
  AND token = 'C5787Y08+JanwwU3zhxxsLYLMvATGA6uz7DDtZ8lv40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}