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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c541a6c95072e93511108d98f7cd618737aa6d6f3f84e9c3d56c4ab00fc72e' 
  AND token = 'uVJC9341aK4c49BkDnKAMwuVh3fIO4JIHk+tpnVEvi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}