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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5d97db82422d2b50a16a2ef52d136da5db03e3d4faab2ba416fa95cf499ebf' 
  AND token = 'r1N5gMZrU8djvGiapMoG7ZrvbQIqMeOFhhzvK4c4rVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}