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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c18aa269852693d55df8d3778b440c4f20a3363b1507db40b1f6314e46d9666f' 
  AND token = '6djqtSExnj+UxUlq0EqYoomM6wERnxdiQpHHhnlJFnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}