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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5436af865b5b1c00a1da843631f6aa1538979a32099fb2bcda0e8fba44099b99' 
  AND token = '4HjlKINlBWJOFjvLRk81ygLDnmgI3J9lYGy51C5+LC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}