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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8839b0b1ab39f46628d9d507bcb7e4c44bfb304c2a2b02b904b25777f9f9e318' 
  AND token = 'dtk0W1PKrUgs0+CCaTS0SaDhQ9+lgMRH4x+1IRsjH9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}