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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25eab88a8e5084c51e3abbdef9ba0f4e4a6a5ef9460ed4c4769c44196ff1c73a' 
  AND token = 'npS4aTPnaUbPEmYAxa4bM21eGMdrtRqOWrDiwADD8oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}