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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ea780152fc00e9d186dcc25adb2c68d1aa1044de01bb8fd4d3b0d863679733' 
  AND token = 'A/RG3w0fADe0WfgxDy5wx5jIa5oQPgSWM4WuDokahTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}