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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb67c8def6004e0992e4e656af1bcbdb2ab3a47a8998ffdbf764cce01c0c5a0' 
  AND token = 'hGm41yJf+tZ2jrv0RayCvPmLUHWX802hIwN98GYj0LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}