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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816c1745b5639d15c2c3c7073879a90febd19edaf01fd77a75bb7ddd78ea6e2a' 
  AND token = '4KfdaRnFPyyMw5HDepS03vPkwEgug2hxfwEkOBLvI2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}