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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48f6f77bbcf58caf3582f2b843347a4074ae7557cbaac007672974527dfbdb1' 
  AND token = 'qJCWSN1R98MO1MN30Xc2VlnWWo2dr1gQ1XU5bA01cdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}