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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390b0afb06216f1cece6d8b728f38566488ce857afc7f4e4006dee0d8368e037' 
  AND token = 'e2u/QCawrUn/9R3q8Vh8ZjvYzScSxyx/O3T6QjSkp74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}