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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa93f2db634bb6e0c39e302cde30686a99a703c6bc2c29f42bb218ad5f4125c' 
  AND token = 'Z+Z3jM66Ab6cxHgXW031GH77W05wXnSPOvtXeVUcZWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}