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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ca743b0f9dd8f0ca5f8432ec8a82179e68cb9e07002f4bd41145ceb31096cf' 
  AND token = 'd+uDZsAc9o9Uexi1zqp6yDvWOMny6K0KKEVrlXnbL7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}