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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f17f92f20a7642100111e05cb7e9dca556e9cbb947f97184dd4d3704534c6e' 
  AND token = '4gPDtygt8hNKhF4RGt5FQ0s65msRkgR00FpcC8xVTss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}