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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5a9399f2934f0d49a23495740e613cb6d4b6c03b00c3675e67fba4dcd9c545' 
  AND token = 'MPCIF54GIRbhuL5OVZv5RkWPJo5rJF1iYTucpsGaMWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}