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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab000c1ef7810ad81245d8ebd058d3d88b491c30ba2c49c90894cc6d0ee6b165' 
  AND token = 'HiZEfZKairWxXKQLYXsae3eCkABp+fmnCcFiZFzg5GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}