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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b72085d9f3114a7b31d055ec4083bbdc661cd0e86320695249cff3575237ab' 
  AND token = 'IBP0lXYeJUoGv7YNoA0A0yUBwAtVQoQIqdeiH6uI3WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}