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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85614e28a6509b89fa90702546471b5b9d2bd4e40d1a4917c58597404383503e' 
  AND token = '51e5jbFYMBTUGbvXMpAbFTu0JC2SwS0POm1QfLzjeUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}