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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffd96d0dbb2a5edc5c9978b7f639384558dd8dae0b0b4d3c5590090598dc10a' 
  AND token = 'MxauxVdwS10a/btO1CDH8AXSkT9e+ZzQayretOyjLzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}