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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14965c681502bf0dbbd2ea90a7e4306e01e8bf4a762632afa52f44375e7325d' 
  AND token = 'rPna6k8gBNtlZZCfvyKdkyILJFHyInZn+6B8aC3M4po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}