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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceb1b4f8cc2e08c8a26ccf651bb5e9996281486e2177fd614a2f5a0d2715b5d6' 
  AND token = 'ZUlYu2ZBFMygHf9wNwJ++NeO50+kcHo1MYAWimg44z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}