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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb20f040a78f5c1cd2611313602677ac43d9d24a3907cd8a7822df2f7e4bd4e' 
  AND token = 'Gir5LmZ+pEHpxm7Lsu2GFuvP/5d3to41MA8V1NLAEZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}