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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9080a210f832806d9c6ad42a6bd90748b87abe4c33573784a72b7f1b71f779a5' 
  AND token = 'sf2AEnvLs0ev3x8joNGzRPmNG19CpINmPUgZ+9puf38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}