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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c309364c1816bbf7965e8c61aa9b982f3ea6154fe78084acf3369886c86abcd6' 
  AND token = 'vvDpCbqa/HEoi2n9XSC70o5X9zOqWPLUSohRy2sODnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}