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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178e36bb0e722155266453cd61485683b5d72da5e377fe94677d054420ea6fb0' 
  AND token = 'uChWNevZobCQIT+M3NrUjv6386mnAtvCLHlB3Xzq9+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}