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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b37f4e06804d0acdae4e01bc35fca9907970a4c5721e1c1a03329c0c0feb58' 
  AND token = 'DGE3etmrKFor7kuRPVT4oIXkB/VszUKMoJuRk3L+DnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}