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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c74e5cb4eddfdfd9336a227fa536f603fe1e2043e32a22082e3caf04fe796a' 
  AND token = 'McAWQO1z6IRo1MJQMoEX2voW8Kej10GK3oPIsz92JZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}