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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a49ef57d4ec6749a3d15f12eafa3d5d39866c1af8ecab3f4e1d486c3fb0a06' 
  AND token = 'Ku00qu+uyDssBhw3a8GwB149AmSAm+QXNB9Dvp6Fzm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}