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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd6dcede5a9b2f90557f05a51723e8387bef4fa70d8abc80b00b5e69d1cf8291' 
  AND token = 'OpV6dAGxfxb9kI8bc03B5FrOXByBPaqdFnSvw8VWeH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}