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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8e9753cdb7de48c4d070a7e122da6e2b5a643d9e542950ed5b25e2b3b2e582' 
  AND token = 'whtl3eDYM+gs6PAHUaF6bZd/LYG3RDIUSJmfFX4U4Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}