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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0137d3c97fa258db0dc43d910d3b1bad39dd501120aa36b17280308833bcaeb1' 
  AND token = 'NXxE9DfOUeh6h26me6at8d6njTY0xh0c1mtMJwZ/Dq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}