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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d82888e51b0e36a2970bc678db11210f8dc45c008ed478e7f2f90ad52a78de3' 
  AND token = 'ofyWJZ0abuqge+STugh9vOOY/s3mBJeiUFf47B3ylZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}