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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daecf4d231300167d1d1a801c66b40c3f3d73493edc09d1ee7ecdddb1e8328ad' 
  AND token = 'Ct/7xR80ZGLM+xw3xN5i+snSOlN4MVHTlkD6yoWD+wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}