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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357d44a31ed59e3e45e49e6c4d5063a7e2b86ec4cef73f2689cd440e90b44d78' 
  AND token = 'F+Na7iPbv9IuyzEmrf9x5dVYgM8sim5K8dn1TygT5I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}