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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd4565e6e7ae05a75e26731148239adc735999c605d0e80ddcd1476db7902c8e' 
  AND token = 'UAQyQHE1Iu8zaqHaasdQWqokVz7riPisdMC/EA0BkiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}